Improving Cognitive Health and Aging through Nutrition and Gut Elevation

I-CHANGE research program - Improving Cognitive Health and Aging through Nutrition and Gut Elevation. As we grow thru different stages of our lifespan, our gut biome also evolves and ages with us. As we get older, our gut biome undergoes senescence and becomes less diverse and resilient thereby making us vulnerable to neurocognitive disorders due to dysregulated gut-brain communication. Studies show that specific prudent dietary patterns may prevent and/or reduce the magnitude of this gut-brain impairment by fostering and nurturing a diverse and robust gut biome profile. Our I-CHANGE program aims to discover and test (in preclinical and clinical settings) such dietary patterns that may prevent or ameliorate aging-associated neurocognitive decline via maintaining a healthier gut biome.